As announced in the March 7th issue of the Wisconsin State Journal, Dr. John Fleming, a leading neurologist at the UW Hospital, is initiating an investigator-initiated IND clinical trial to assess the safety and efficacy of Trichuris suis ova (TSO) in the treatment of Multiple Sclerosis (MS). Dr. Fleming's trial is funded by the Multiple Sclerosis Society, and is the first of its kind within the United States.

The concept of using TSO therapy to treat MS was sparked by evidence showing TSO boosts regulatory T cells, and may therefore be able to down-modulate pathways observed in Multiple Sclerosis (as well as in Crohn's Disease). Indeed, in a February 2007 publication in Annals of Neurology by Correale and Farez, et al. MS patients chronically populated with helminths experienced a significantly more favorable course of the disease, as compared with worm-free MS patients................

For the complete report please go to MSRC: MS Research News : Drugs : Further Possible MS Drugs and Treatments - http://www.msrc.co.uk/index.cfm?fuseaction=show&pageid=1397